Systems biology meets toxicology

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Systems biology meets platelet biology.

tion was associated with an observable survival benefit and delay in progression to AIDS among HIV-1–infected IDUs. 3 While HTLV-I has been definitively proven to cause adult T-cell leukemia/lym-phoma and a progressive neurodegenerative illness known as tropical spastic parapare-sis/HTLV-I–associated myelopathy (TSP/ HAM), a causal role for HTLV-II with either leukemia or TSP/HAM is much less w...

متن کامل

Systems biology meets behavior.

E arly scientists were drawn to the study of insects in part because of the marvelous notion that their full behavioral repertoire was orchestrated from within. This was stated most succinctly perhaps by Spalding (1873): “When, as by a miracle, the lovely butterfly bursts from the chrysalis fullwinged and perfect, . . .it has, for the most part, nothing to learn, because its little life flows f...

متن کامل

Stem cell biology meets systems biology.

Stem cells and their descendents are the building blocks of life. How stem cell populations guarantee their maintenance and/or self-renewal, and how individual stem cells decide to transit from one cell stage to another to generate different cell types are long-standing and fascinating questions in the field. Here, we review the discussions that took place at a recent EMBO conference in Cambrid...

متن کامل

Systems biology meets chromatin function

Introduction It is clear that DNA sequence and transcription factor availability alone are not sufficient for effective gene regulation in eukaryotes. Epigenetic factors at various levels also have an essential role: for example, DNA methylation and histone modifications form the molecular basis of gene regulation by creating chromatin microenvironments that promote or prevent transcription. Ge...

متن کامل

Applicability of computational systems biology in toxicology.

Systems biology as a research field has emerged within the last few decades. Systems biology, often defined as the antithesis of the reductionist approach, integrates information about individual components of a biological system. In integrative systems biology, large data sets from various sources and databases are used to model and predict effects of chemicals on, for instance, human health. ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Archives of Toxicology

سال: 2012

ISSN: 0340-5761,1432-0738

DOI: 10.1007/s00204-012-0900-9